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Dock7 regulates AKT and mTOR/S6K activity required for the transformed phenotypes and survival of cancer cells
Cancer cells, both within a developing tumor and during metastatic spread, encounter many stresses that require adaptive mechanisms to survive and maintain malignant progression. Here we describe a signaling complex involving the small GTPase Cdc42 and Dock7, a Cdc42/Rac GEF and unique Cdc42-effecto...
Autores principales: | Teran, Oriana Y., Zanotelli, Matthew R., Lin, Miao-chong Joy, Cerione, Richard A., Wilson, Kristin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881951/ https://www.ncbi.nlm.nih.gov/pubmed/36711811 http://dx.doi.org/10.1101/2023.01.03.522657 |
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