Simultaneous proteome localization and turnover analysis reveals spatiotemporal dynamics of unfolded protein responses

The functions of proteins depend on their spatial and temporal distributions, which are not directly measured by static protein abundance. Under protein misfolding stress, the unfolded protein response (UPR) pathway remediates proteostasis in part by altering the turnover kinetics and spatial distri...

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Detalles Bibliográficos
Autores principales: Currie, Jordan, Manda, Vyshnavi, Hidalgo, Veronica, Ludwig, R. W., Lam, Maggie P. Y., Lau, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881985/
https://www.ncbi.nlm.nih.gov/pubmed/36711879
http://dx.doi.org/10.1101/2023.01.04.521821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881985/
https://www.ncbi.nlm.nih.gov/pubmed/36711879
http://dx.doi.org/10.1101/2023.01.04.521821

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