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Simultaneous proteome localization and turnover analysis reveals spatiotemporal dynamics of unfolded protein responses
The functions of proteins depend on their spatial and temporal distributions, which are not directly measured by static protein abundance. Under protein misfolding stress, the unfolded protein response (UPR) pathway remediates proteostasis in part by altering the turnover kinetics and spatial distri...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881985/ https://www.ncbi.nlm.nih.gov/pubmed/36711879 http://dx.doi.org/10.1101/2023.01.04.521821 |