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Neutrophil extracellular trap stabilization by platelet factor 4 reduces thrombogenicity and endothelial cell injury

Neutrophil extracellular traps (NETs) are abundant in sepsis, and proposed NET-directed therapies in sepsis prevent their formation or accelerate degradation. Yet NETs are important for microbial entrapment, as NET digestion liberates pathogens and NET degradation products (NDPs) that deleteriously...

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Detalles Bibliográficos
Autores principales: Ngo, Anh T. P., Sarkar, Amrita, Yarovoi, Irene, Levine, Nate D., Bochenek, Veronica, Zhao, Guohua, Rauova, Lubica, Kowalska, M. Anna, Eckart, Kaitlyn, Mangalmurti, Nilam S., Rux, Ann, Cines, Douglas B., Poncz, Mortimer, Gollomp, Kandace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881987/
https://www.ncbi.nlm.nih.gov/pubmed/36711969
http://dx.doi.org/10.1101/2023.01.09.522931