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Automated Enrichment of Phosphotyrosine Peptides for High-Throughput Proteomics

Phosphotyrosine (pY) enrichment is critical for expanding fundamental and clinical understanding of cellular signaling by mass spectrometry-based proteomics. However, current pY enrichment methods exhibit a high cost per sample and limited reproducibility due to expensive affinity reagents and manua...

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Detalles Bibliográficos
Autores principales: Chang, Alexis, Leutert, Mario, Rodriguez-Mias, Ricard A., Villén, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881991/
https://www.ncbi.nlm.nih.gov/pubmed/36711935
http://dx.doi.org/10.1101/2023.01.05.522335