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Understanding and evaluating ambiguity in single-cell and single-nucleus RNA-sequencing
Recently, a new modification has been proposed by Hjörleifsson and Sullivan et al. to the model used to classify the splicing status of reads (as spliced (mature), unspliced (nascent), or ambiguous) in single-cell and single-nucleus RNA-seq data. Here, we evaluate both the theoretical basis and prac...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881993/ https://www.ncbi.nlm.nih.gov/pubmed/36711921 http://dx.doi.org/10.1101/2023.01.04.522742 |