Cargando…

The QseB response regulator imparts tolerance to positively charged antibiotics by controlling metabolism and minor changes to LPS

The modification of lipopolysaccharide (LPS) in Escherichia coli and Salmonella spp. is primarily controlled by the two-component system PmrAB. LPS modification allows bacteria to avoid killing by positively charged antibiotics like polymyxin B. We previously demonstrated that in uropathogenic E. co...

Descripción completa

Detalles Bibliográficos
Autores principales: Hurst, Melanie N., Beebout, Connor J., Hollingsworth, Alexis, Guckes, Kirsten R., Purcell, Alexandria, Bermudez, Tomas A., Williams, Diamond, Reasoner, Seth A., Trent, M. Stephen, Hadjifrangiskou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882033/
https://www.ncbi.nlm.nih.gov/pubmed/36711705
http://dx.doi.org/10.1101/2023.01.10.523522