Ethanolaminephosphate cytidyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major

Glycerophospholipids including phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are vital components of biological membranes. Trypanosomatid parasites of the genus Leishmania can acquire PE and PC via de novo synthesis and the uptake/remodeling of host lipids. In this study, we investigate...

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Detalles Bibliográficos
Autores principales: Basu, Somrita, Pawlowic, Mattie, Hsu, Fong-Fu, Thomas, Geoff, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882048/
https://www.ncbi.nlm.nih.gov/pubmed/36712124
http://dx.doi.org/10.1101/2023.01.10.523530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882048/
https://www.ncbi.nlm.nih.gov/pubmed/36712124
http://dx.doi.org/10.1101/2023.01.10.523530

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