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Sickle cell disease patient plasma sensitizes iPSC-derived sensory neurons from sickle cell disease patients

Individuals living with sickle cell disease (SCD) experience severe recurrent acute and chronic pain. In order to develop novel therapies, it is necessary to better understand the neurobiological mechanisms underlying SCD pain. There are many barriers to gaining mechanistic insight into pathogenic S...

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Detalles Bibliográficos
Autores principales: Allison, Reilly L., Burand, Anthony, Torres, Damaris Nieves, Brandow, Amanda M., Stucky, Cheryl L., Ebert, Allison D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882050/
https://www.ncbi.nlm.nih.gov/pubmed/36711992
http://dx.doi.org/10.1101/2023.01.10.523446