Polyploid yeast are dependent on elevated levels of Mps1 for successful chromosome segregation

Tumor cell lines with elevated chromosome numbers frequently have correlated elevations of Mps1 expression and these tumors are more dependent on Mps1 activity for their survival than control cell lines. Mps1 is a conserved kinase involved in controlling aspects of chromosome segregation in mitosis...

Descripción completa

Detalles Bibliográficos
Autores principales: Meyer, Régis E, Sartin, Ashlea, Gish, Madeline, Harsha, Jillian, Wilkie, Emily, Haworth, Dawson, LaVictoire, Rebecca, Alberola, Isabel, Chuong, Hoa H, Gorbsky, Gary J, Dawson, Dean S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882063/
https://www.ncbi.nlm.nih.gov/pubmed/36712123
http://dx.doi.org/10.1101/2023.01.09.523325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882063/
https://www.ncbi.nlm.nih.gov/pubmed/36712123
http://dx.doi.org/10.1101/2023.01.09.523325

Ejemplares similares