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Notch signaling regulates immunosuppressive tumor-associated macrophage function in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA) continues to have a dismal prognosis. The poor survival of patients with PDA has been attributed to a high rate of early metastasis and low efficacy of current therapies, which partly result from its complex immunosuppressive tumor microenvironment. Previous st...

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Detalles Bibliográficos
Autores principales: Yan, Wei, Steele, Nina G., Kemp, Samantha B., Menjivar, Rosa E., Du, Wenting, Carpenter, Eileen S., Donahue, Katelyn L., Brown, Kristee L., Irizarry-Negron, Valerie, Yang, Sion, Burns, William R., Zhang, Yaqing, di Magliano, Marina Pasca, Bednar, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882066/
https://www.ncbi.nlm.nih.gov/pubmed/36711890
http://dx.doi.org/10.1101/2023.01.11.523584