The neurodevelopmental transcriptome of the Drosophila melanogaster microcephaly gene abnormal spindle reveals a role for temporal transcription factors and the immune system in regulating brain size

The coordination of cellular behaviors during neurodevelopment is critical for determining the form, function, and size of the central nervous system. Mutations in the vertebrate Abnormal Spindle-Like, Microcephaly Associated (ASPM) gene and its Drosophila melanogaster ortholog abnormal spindle (asp...

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Detalles Bibliográficos
Autores principales: Mannino, Maria C., Bartels Cassidy, Mercedes, Florez, Steven, Rusan, Zeid, Chakraborty, Shalini, Schoborg, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882087/
https://www.ncbi.nlm.nih.gov/pubmed/36711768
http://dx.doi.org/10.1101/2023.01.09.523369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882087/
https://www.ncbi.nlm.nih.gov/pubmed/36711768
http://dx.doi.org/10.1101/2023.01.09.523369

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