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The neurodevelopmental transcriptome of the Drosophila melanogaster microcephaly gene abnormal spindle reveals a role for temporal transcription factors and the immune system in regulating brain size
The coordination of cellular behaviors during neurodevelopment is critical for determining the form, function, and size of the central nervous system. Mutations in the vertebrate Abnormal Spindle-Like, Microcephaly Associated (ASPM) gene and its Drosophila melanogaster ortholog abnormal spindle (asp...
Autores principales: | Mannino, Maria C., Bartels Cassidy, Mercedes, Florez, Steven, Rusan, Zeid, Chakraborty, Shalini, Schoborg, Todd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882087/ https://www.ncbi.nlm.nih.gov/pubmed/36711768 http://dx.doi.org/10.1101/2023.01.09.523369 |
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