Pressure and ultrasound activate mechanosensitive TRAAK K(+) channels through increased membrane tension

TRAAK is a mechanosensitive two-pore domain K(+) (K2P) channel found in nodes of Ranvier within myelinated axons. It displays low leak activity at rest and is activated up to one hundred-fold by increased membrane tension. Structural and functional studies have led to physical models for channel gat...

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Detalles Bibliográficos
Autores principales: Sorum, Ben, Docter, Trevor, Panico, Vincent, Rietmeijer, Robert A., Brohawn, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882092/
https://www.ncbi.nlm.nih.gov/pubmed/36712118
http://dx.doi.org/10.1101/2023.01.11.523644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882092/
https://www.ncbi.nlm.nih.gov/pubmed/36712118
http://dx.doi.org/10.1101/2023.01.11.523644

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