Cargando…
Pressure and ultrasound activate mechanosensitive TRAAK K(+) channels through increased membrane tension
TRAAK is a mechanosensitive two-pore domain K(+) (K2P) channel found in nodes of Ranvier within myelinated axons. It displays low leak activity at rest and is activated up to one hundred-fold by increased membrane tension. Structural and functional studies have led to physical models for channel gat...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882092/ https://www.ncbi.nlm.nih.gov/pubmed/36712118 http://dx.doi.org/10.1101/2023.01.11.523644 |