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Ketolysis is Required for the Proper Development and Function of the Somatosensory Nervous System

Ketogenic diets are emerging as protective interventions in preclinical and clinical models of somatosensory nervous system disorders. Additionally, dysregulation of succinyl-CoA 3-oxoacid CoA-transferase 1 (SCOT, encoded by Oxct1), the fate-committing enzyme in mitochondrial ketolysis, has recently...

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Detalles Bibliográficos
Autores principales: Enders, Jonathan, Jack, Jarrid, Thomas, Sarah, Lynch, Paige, Lasnier, Sarah, Cao, Xin, Swanson, M Taylor, Ryals, Janelle M, Thyfault, John P., Puchalska, Patrycja, Crawford, Peter A., Wright, Douglas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882096/
https://www.ncbi.nlm.nih.gov/pubmed/36711538
http://dx.doi.org/10.1101/2023.01.11.523492