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Ketolysis is Required for the Proper Development and Function of the Somatosensory Nervous System
Ketogenic diets are emerging as protective interventions in preclinical and clinical models of somatosensory nervous system disorders. Additionally, dysregulation of succinyl-CoA 3-oxoacid CoA-transferase 1 (SCOT, encoded by Oxct1), the fate-committing enzyme in mitochondrial ketolysis, has recently...
Autores principales: | Enders, Jonathan, Jack, Jarrid, Thomas, Sarah, Lynch, Paige, Lasnier, Sarah, Cao, Xin, Swanson, M Taylor, Ryals, Janelle M, Thyfault, John P., Puchalska, Patrycja, Crawford, Peter A., Wright, Douglas E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882096/ https://www.ncbi.nlm.nih.gov/pubmed/36711538 http://dx.doi.org/10.1101/2023.01.11.523492 |
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