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Selection of optimal cell lines for high-content phenotypic screening

High-content microscopy offers a scalable approach to screen against multiple targets in a single pass. Prior work has focused on methods to select “optimal” cellular readouts in microscopy screens. However, methods to select optimal cell line models have garnered much less attention. Here, we provi...

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Detalles Bibliográficos
Autores principales: Heinrich, Louise, Kumbier, Karl, Li, Li, Altschuler, Steven P., Wu, Lani F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882115/
https://www.ncbi.nlm.nih.gov/pubmed/36711978
http://dx.doi.org/10.1101/2023.01.11.523662