HepaRG cells undergo increased levels of post-differentiation patterning in physiologic conditions when maintained as 3D cultures in paper-based scaffolds

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Monolayer cultures of hepatocytes lack many aspects of the liver sinusoid, including a tissue-level organization that results from extracellular matrix interactions and gradients of soluble molecules that span from the portal triad to the central vein. We measured the activity and transcript levels...

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Detalles Bibliográficos
Autores principales: Diprospero, Thomas J., Brown, Lauren G., Fachko, Trevor D., Lockett, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882149/
https://www.ncbi.nlm.nih.gov/pubmed/36711996
http://dx.doi.org/10.1101/2023.01.16.524330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882149/
https://www.ncbi.nlm.nih.gov/pubmed/36711996
http://dx.doi.org/10.1101/2023.01.16.524330

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