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End Binding protein 1 promotes specific motor-cargo association in the cell body prior to axonal delivery of Dense Core Vesicles

Axonal transport is key to neuronal function. Efficient transport requires specific motor-cargo association in the soma, yet the mechanisms regulating this early step remain poorly understood. We found that EBP-1, the C. elegans ortholog of the canonical microtubule end binding protein EB1, promotes...

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Detalles Bibliográficos
Autores principales: Park, Junhyun, Miller, Kenneth G., De Camilli, Pietro, Yogev, Shaul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882160/
https://www.ncbi.nlm.nih.gov/pubmed/36711860
http://dx.doi.org/10.1101/2023.01.12.523768