Defining T cell receptor repertoires using nanovial-based affinity and functional screening

The ability to selectively bind to antigenic peptides and secrete cytokines can define populations of cells with therapeutic potential in emerging T cell receptor (TCR) immunotherapies. We leverage cavity-containing hydrogel microparticles, called nanovials, each coated with millions of peptide-majo...

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Detalles Bibliográficos
Autores principales: Koo, Doyeon, Mao, Zhiyuan, Dimatteo, Robert, Tsubamoto, Natalie, Noguchi, Miyako, McLaughlin, Jami, Tran, Wendy, Lee, Sohyung, Cheng, Donghui, de Rutte, Joseph, Sojo, Giselle Burton, Witte, Owen N., Di Carlo, Dino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882161/
https://www.ncbi.nlm.nih.gov/pubmed/36711524
http://dx.doi.org/10.1101/2023.01.17.524440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882161/
https://www.ncbi.nlm.nih.gov/pubmed/36711524
http://dx.doi.org/10.1101/2023.01.17.524440

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