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Bidirectional multiciliated cell extrusion is controlled by Notch driven basal extrusion and Piezo 1 driven apical extrusion

Xenopus embryos are covered with a complex epithelium containing numerous multiciliated cells (MCCs). During late stage development there is a dramatic remodeling of the epithelium that involves the complete loss of MCCs. Cell extrusion is a well-characterized process for driving cell loss while mai...

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Detalles Bibliográficos
Autores principales: Ventrella, Rosa, Kim, Sun K., Sheridan, Jennifer, Grata, Aline, Bresteau, Enzo, Hassan, Osama, Suva, Eve E., Walentek, Peter, Mitchell, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882179/
https://www.ncbi.nlm.nih.gov/pubmed/36711534
http://dx.doi.org/10.1101/2023.01.12.523838