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A single amino acid polymorphism in natural Metchnikowin alleles of Drosophila results in systemic immunity and life history tradeoffs

Antimicrobial peptides (AMPs) are at the interface of interactions between hosts and microbes and are therefore expected to be fast evolving in a coevolutionary arms race with pathogens. In contrast, previous work demonstrated that one AMP, Metchikowin (Mtk), has a single residue that segregates as...

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Detalles Bibliográficos
Autores principales: Perlmutter, Jessamyn I., Chapman, Joanne R., Wilkinson, Mason C., Nevarez-Saenz, Isaac, Unckless, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882182/
https://www.ncbi.nlm.nih.gov/pubmed/36712113
http://dx.doi.org/10.1101/2023.01.16.524277