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A single amino acid polymorphism in natural Metchnikowin alleles of Drosophila results in systemic immunity and life history tradeoffs
Antimicrobial peptides (AMPs) are at the interface of interactions between hosts and microbes and are therefore expected to be fast evolving in a coevolutionary arms race with pathogens. In contrast, previous work demonstrated that one AMP, Metchikowin (Mtk), has a single residue that segregates as...
Autores principales: | Perlmutter, Jessamyn I., Chapman, Joanne R., Wilkinson, Mason C., Nevarez-Saenz, Isaac, Unckless, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882182/ https://www.ncbi.nlm.nih.gov/pubmed/36712113 http://dx.doi.org/10.1101/2023.01.16.524277 |
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