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The psychosis risk factor RBM12 encodes a novel repressor of GPCR/cAMP signal transduction

RBM12 is a high-penetrance risk factor for familial schizophrenia and psychosis, yet its precise cellular functions and the pathways to which it belongs are not known. We utilize two complementary models, HEK293 cells and human iPSC-derived neurons, and delineate RBM12 as a novel repressor of the G...

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Detalles Bibliográficos
Autores principales: Semesta, Khairunnisa M, Garces, Angelica, Tsvetanova, Nikoleta G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882185/
https://www.ncbi.nlm.nih.gov/pubmed/36711667
http://dx.doi.org/10.1101/2023.01.12.523776