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Extensive and Persistent Extravascular Dermal Fibrin Deposition Characterizes Systemic Sclerosis

Systemic sclerosis (SSc) is an autoimmune disease characterized by progressive multiorgan fibrosis. While the cause of SSc remains unknown, a perturbed vasculature is considered a critical early step in the pathogenesis. Using fibrinogen as a marker of vascular leakage, we found extensive extravascu...

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Detalles Bibliográficos
Autores principales: Browning, Jeffrey L., Bhawan, Jag, Tseng, Anna, Crossland, Nicholas, Bujor, Andreea M, Akassoglou, Katerina, Assassi, Shervin, Skaug, Brian, Ho, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882194/
https://www.ncbi.nlm.nih.gov/pubmed/36711912
http://dx.doi.org/10.1101/2023.01.16.523256