Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators

Pharmacological activation of the activating transcription factor 6 (ATF6) arm of the Unfolded Protein Response (UPR) has proven useful for ameliorating proteostasis deficiencies in a variety of etiologically diverse diseases. Previous high-throughput screening efforts identified the small molecule...

Descripción completa

Detalles Bibliográficos
Autores principales: Kline, Gabriel M., Paxman, Ryan J, Lin, Chung-Yon, Madrazo, Nicole, Grandjean, Julia M., Lee, Kyunga, Nugroho, Karina, Powers, Evan T., Wiseman, R. Luke, Kelly, Jeffery W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882204/
https://www.ncbi.nlm.nih.gov/pubmed/36712115
http://dx.doi.org/10.1101/2023.01.16.524237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882204/
https://www.ncbi.nlm.nih.gov/pubmed/36712115
http://dx.doi.org/10.1101/2023.01.16.524237

Ejemplares similares