Bromodomain-containing Protein 4 Regulates Innate Inflammation in Airway Epithelial Cells via Modulation of Alternative Splicing

Bromodomain-containing Protein 4 (BRD4) is a transcriptional regulator which coordinates gene expression programs controlling cancer biology, inflammation, and fibrosis. In airway viral infection, non-toxic BRD4-specific inhibitors (BRD4i) block the release of pro-inflammatory cytokines and prevent...

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Detalles Bibliográficos
Autores principales: Mann, Morgan, Fu, Yao, Xu, Xiaofang, Roberts, David S., Li, Yi, Zhou, Jia, Ge, Ying, Brasier, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882210/
https://www.ncbi.nlm.nih.gov/pubmed/36711789
http://dx.doi.org/10.1101/2023.01.17.524257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882210/
https://www.ncbi.nlm.nih.gov/pubmed/36711789
http://dx.doi.org/10.1101/2023.01.17.524257

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