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Actin nucleators safeguard replication forks by limiting nascent strand degradation

Accurate genome replication is essential for all life and a key mechanism of disease prevention, underpinned by the ability of cells to respond to replicative stress (RS) and protect replication forks. These responses rely on the formation of Replication Protein A (RPA)-single stranded (ss) DNA comp...

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Detalles Bibliográficos
Autores principales: Nieminuszczy, Jadwiga, Martin, Peter R., Broderick, Ronan, Krwawicz, Joanna, Kanellou, Alexandra, Mocanu, Camelia, Bousgouni, Vicky, Smith, Charlotte, Wen, Kuo-Kuang, Woodward, Beth L., Bakal, Chris, Shackley, Fiona, Aguilera, Andres, Stewart, Grant S., Vyas, Yatin M., Niedzwiedz, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882250/
https://www.ncbi.nlm.nih.gov/pubmed/36711944
http://dx.doi.org/10.1101/2023.01.12.523639