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Phenome-wide analysis identifies parent-of-origin effects on the human methylome associated with changes in the rate of aging

Variation in the rate at which humans age may be rooted in early life events acting through genomic regions that are influenced by such events and subsequently are related to health phenotypes in later life. The parent-of-origin-effect (POE)-regulated methylome includes regions either enriched for g...

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Detalles Bibliográficos
Autores principales: Gao, Chenhao, Amador, Carmen, Walker, Rosie M., Campbell, Archie, Madden, Rebecca A, Adams, Mark J., Bai, Xiaomeng, Liu, Ying, Li, Miaoxin, Hayward, Caroline, Porteous, David J., Shen, Xueyi, Evans, Kathryn L., Haley, Chris S., McIntosh, Andrew M., Navarro, Pau, Zeng, Yanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882261/
https://www.ncbi.nlm.nih.gov/pubmed/36711749
http://dx.doi.org/10.1101/2023.01.18.524653