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Generation of human alveolar epithelial type I cells from pluripotent stem cells

In the distal lung, alveolar epithelial type I cells (AT1s) comprise the vast majority of alveolar surface area and are uniquely flattened to allow the diffusion of oxygen into the capillaries. This structure along with a quiescent, terminally differentiated phenotype has made AT1s particularly chal...

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Detalles Bibliográficos
Autores principales: Burgess, Claire L, Huang, Jessie, Bawa, Pushpinder, Alysandratos, Konstantinos-Dionysios, Minakin, Kasey, Morley, Michael P, Babu, Apoorva, Villacorta-Martin, Carlos, Hinds, Anne, Thapa, Bibek R, Wang, Feiya, Matschulat, Adeline M, Morrisey, Edward E, Varelas, Xaralabos, Kotton, Darrell N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882278/
https://www.ncbi.nlm.nih.gov/pubmed/36711505
http://dx.doi.org/10.1101/2023.01.19.524655