Cargando…

Combining protein sequences and structures with transformers and equivariant graph neural networks to predict protein function

MOTIVATION: Millions of protein sequences have been generated by numerous genome and transcriptome sequencing projects. However, experimentally determining the function of the proteins is still a time consuming, low-throughput, and expensive process, leading to a large protein sequence-function gap....

Descripción completa

Detalles Bibliográficos
Autores principales: Boadu, Frimpong, Cao, Hongyuan, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882282/
https://www.ncbi.nlm.nih.gov/pubmed/36711471
http://dx.doi.org/10.1101/2023.01.17.524477