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Sensitized piRNA reporter identifies multiple RNA processing factors involved in piRNA-mediated gene silencing

Metazoans guard their germlines against transposons and other foreign transcripts with PIWI-interacting RNAs (piRNAs). Due to the robust heritability of the silencing initiated by piRNAs in C.elegans, previous screens using Caenorhabditis elegans were strongly biased to uncover members of this pathw...

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Detalles Bibliográficos
Autores principales: Brown, Jordan, Zhang, Donglei, Chen, Wenjun, Lee, Heng-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882300/
https://www.ncbi.nlm.nih.gov/pubmed/36712000
http://dx.doi.org/10.1101/2023.01.22.525052