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Sensitized piRNA reporter identifies multiple RNA processing factors involved in piRNA-mediated gene silencing
Metazoans guard their germlines against transposons and other foreign transcripts with PIWI-interacting RNAs (piRNAs). Due to the robust heritability of the silencing initiated by piRNAs in C.elegans, previous screens using Caenorhabditis elegans were strongly biased to uncover members of this pathw...
Autores principales: | Brown, Jordan, Zhang, Donglei, Chen, Wenjun, Lee, Heng-Chi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882300/ https://www.ncbi.nlm.nih.gov/pubmed/36712000 http://dx.doi.org/10.1101/2023.01.22.525052 |
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