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Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection

Mycobacterium tuberculosis (Mtb) infects cells in multiple lung myeloid cell subsets and causes chronic infection despite innate and adaptive immune responses. However, the mechanisms allowing Mtb to evade elimination are not fully understood. Here, using new methods, we determined that after T cell...

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Detalles Bibliográficos
Autores principales: Zheng, Weihao, Chang, I-Chang, Limberis, Jason, Budzik, Jonathan M., Zha, B. Shoshana, Howard, Zach, Chen, Lucas, Ernst, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882350/
https://www.ncbi.nlm.nih.gov/pubmed/36711606
http://dx.doi.org/10.1101/2023.01.19.524758