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Comparison of gene set scoring methods for reproducible evaluation of multiple tuberculosis gene signatures

RATIONALE: Many blood-based transcriptional gene signatures for tuberculosis (TB) have been developed with potential use to diagnose disease, predict risk of progression from infection to disease, and monitor TB treatment outcomes. However, an unresolved issue is whether gene set enrichment analysis...

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Detalles Bibliográficos
Autores principales: Wang, Xutao, VanValkenberg, Arthur, Odom-Mabey, Aubrey R., Ellner, Jerrold J., Hochberg, Natasha S., Salgame, Padmini, Patil, Prasad, Johnson, W. Evan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882404/
https://www.ncbi.nlm.nih.gov/pubmed/36711818
http://dx.doi.org/10.1101/2023.01.19.520627