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Genetic association studies using disease liabilities from deep neural networks

The case-control study is a widely used method for investigating the genetic landscape of binary traits. However, the health-related outcome or disease status of participants in long-term, prospective cohort studies such as the UK Biobank are subject to change. Here, we develop an approach for the g...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Sadler, Marie C., Altman, Russ B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882423/
https://www.ncbi.nlm.nih.gov/pubmed/36712099
http://dx.doi.org/10.1101/2023.01.18.23284383