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Tryptophan metabolism determines outcome in tuberculous meningitis: a targeted metabolomic analysis

BACKGROUND: Cellular metabolism is critical for the host immune function against pathogens, and metabolomic analysis may help understand the characteristic immunopathology of tuberculosis. We performed targeted metabolomic analyses in a large cohort of patients with tuberculous meningitis (TBM), the...

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Detalles Bibliográficos
Autores principales: Ardiansyah, Edwin, Pacheco, Julian Avila, Nhat, Le Thanh Hoang, Dian, Sofiati, Vinh, Dao Nguyen, Hai, Hoang Thanh, Bullock, Kevin, Alisjahbana, Bachti, Netea, Mihai G, Estiasari, Riwanti, Tram, Trinh Thi Bich, Donovan, Joseph, Heemskerk, Dorothee, Chau, Tran Thi Hong, Bang, Nguyen Duc, Ganiem, Ahmad Rizal, Ruslami, Rovina, Koeken, Valerie ACM, Hamers, Raph L, Imran, Darma, Maharani, Kartika, Kumar, Vinod, Clish, Clary B., van Crevel, Reinout, Thwaites, Guy, van Laarhoven, Arjan, Thuong, Nguyen Thuy Thuong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882445/
https://www.ncbi.nlm.nih.gov/pubmed/36711829
http://dx.doi.org/10.1101/2023.01.08.23284316