The major TMEM106B dementia risk allele affects TMEM106B protein levels and myelin lipid homeostasis in the ageing human hippocampus

BACKGROUND: The risk for dementia increases exponentially from the seventh decade of life. Identifying and understanding the biochemical changes that sensitize the ageing brain to neurodegeneration will provide new opportunities for dementia prevention and treatment. This study aimed to determine ho...

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Detalles Bibliográficos
Autores principales: Lee, Jun Yup, Harney, Dylan, Kwok, John, Larance, Mark, Don, Anthony Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882607/
https://www.ncbi.nlm.nih.gov/pubmed/36711721
http://dx.doi.org/10.21203/rs.3.rs-2392941/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882607/
https://www.ncbi.nlm.nih.gov/pubmed/36711721
http://dx.doi.org/10.21203/rs.3.rs-2392941/v1

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