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A spatial map of human macrophage niches reveals context-dependent macrophage functions in colon and breast cancer

Tumor-associated macrophages (TAMs) display heterogeneous phenotypes. Yet the exact tissue cues that shape macrophage functional diversity are incompletely understood. Here we discriminate, spatially resolve and reveal the function of five distinct macrophage niches within malignant and benign breas...

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Detalles Bibliográficos
Autores principales: Matusiak, Magdalena, Hickey, John W., Luca, Bogdan, Lu, Guolan, Kidziński, Lukasz, Zhu, Shirley, Colburg, Deana Rae Crystal, Phillips, Darci J., Brubaker, Sky W., Charville, Gregory W., Shen, Jeanne, Nolan, Garry P., Newman, Aaron M., West, Robert B., van de Rijn, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882614/
https://www.ncbi.nlm.nih.gov/pubmed/36711732
http://dx.doi.org/10.21203/rs.3.rs-2393443/v1