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A spatial map of human macrophage niches reveals context-dependent macrophage functions in colon and breast cancer
Tumor-associated macrophages (TAMs) display heterogeneous phenotypes. Yet the exact tissue cues that shape macrophage functional diversity are incompletely understood. Here we discriminate, spatially resolve and reveal the function of five distinct macrophage niches within malignant and benign breas...
Autores principales: | Matusiak, Magdalena, Hickey, John W., Luca, Bogdan, Lu, Guolan, Kidziński, Lukasz, Zhu, Shirley, Colburg, Deana Rae Crystal, Phillips, Darci J., Brubaker, Sky W., Charville, Gregory W., Shen, Jeanne, Nolan, Garry P., Newman, Aaron M., West, Robert B., van de Rijn, Matt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882614/ https://www.ncbi.nlm.nih.gov/pubmed/36711732 http://dx.doi.org/10.21203/rs.3.rs-2393443/v1 |
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