Oleoylethanolamide facilitates PPARa and TFEB signaling and attenuates Ab pathology in a mouse model of Alzheimer’s disease

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Emerging evidence implicates impaired microglia function and dysregulation of lipid metabolism in Alzheimer’s disease (AD). Oleoylethanolamide (OEA), an endogenous lipid and PPARα agonist, has been shown to promote longevity in C. elegans through regulation of lysosome-to-nucleus signaling and cellu...

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Detalles Bibliográficos
Autores principales: Comerota, Michele, Gedam, Manasee, Xiong, Wen, Jin, Feng, Deng, Lisheng, Wang, Meng, Wang, Jin, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882642/
https://www.ncbi.nlm.nih.gov/pubmed/36711875
http://dx.doi.org/10.21203/rs.3.rs-2484513/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882642/
https://www.ncbi.nlm.nih.gov/pubmed/36711875
http://dx.doi.org/10.21203/rs.3.rs-2484513/v1

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