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Oleoylethanolamide facilitates PPARa and TFEB signaling and attenuates Ab pathology in a mouse model of Alzheimer’s disease
Emerging evidence implicates impaired microglia function and dysregulation of lipid metabolism in Alzheimer’s disease (AD). Oleoylethanolamide (OEA), an endogenous lipid and PPARα agonist, has been shown to promote longevity in C. elegans through regulation of lysosome-to-nucleus signaling and cellu...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882642/ https://www.ncbi.nlm.nih.gov/pubmed/36711875 http://dx.doi.org/10.21203/rs.3.rs-2484513/v1 |
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por Comerota, Michele M., Gedam, Manasee, Xiong, Wen, Jin, Feng, Deng, Lisheng, Wang, Meng C., Wang, Jin, Zheng, Hui
Publicado 2023
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Publicado 2023
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Online
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Texto