Origin and Evolution of RAS Oncoprotein Membrane Targeting

KRAS, HRAS and NRAS oncogenes belong to a family of 40 highly homologous genes, which in turn are a subset of a superfamily of >160 genes encoding small GTPases. RAS oncoproteins consist of a globular G-domain (aa1-166) and a 22-23aa unstructured hypervariable region (HVR) that mediates membrane...

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Detalles Bibliográficos
Autores principales: García-España, Antonio, Philips, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882654/
https://www.ncbi.nlm.nih.gov/pubmed/36711820
http://dx.doi.org/10.21203/rs.3.rs-2485219/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882654/
https://www.ncbi.nlm.nih.gov/pubmed/36711820
http://dx.doi.org/10.21203/rs.3.rs-2485219/v1

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