Stereoselective Construction of β-, γ-, and δ-Lactam Rings via Enzymatic C–H Amidation

Lactam rings are found in many biologically active natural products and pharmaceuticals, including important classes of antibiotics. Given their widespread presence in bioactive molecules, methods for the asymmetric synthesis of these molecules, in particular through the selective functionalization...

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Detalles Bibliográficos
Autores principales: Roy, Satyajit, Vargas, David A., Ma, Pengchen, Sengupta, Arkajyoti, Zhu, Ledong, Houk, K. N., Fasan, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882675/
https://www.ncbi.nlm.nih.gov/pubmed/36711830
http://dx.doi.org/10.21203/rs.3.rs-2429100/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882675/
https://www.ncbi.nlm.nih.gov/pubmed/36711830
http://dx.doi.org/10.21203/rs.3.rs-2429100/v1

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