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Stereoselective Construction of β-, γ-, and δ-Lactam Rings via Enzymatic C–H Amidation
Lactam rings are found in many biologically active natural products and pharmaceuticals, including important classes of antibiotics. Given their widespread presence in bioactive molecules, methods for the asymmetric synthesis of these molecules, in particular through the selective functionalization...
Autores principales: | Roy, Satyajit, Vargas, David A., Ma, Pengchen, Sengupta, Arkajyoti, Zhu, Ledong, Houk, K. N., Fasan, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882675/ https://www.ncbi.nlm.nih.gov/pubmed/36711830 http://dx.doi.org/10.21203/rs.3.rs-2429100/v1 |
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