Reduced hepatocyte mitophagy is an early feature of NAFLD pathogenesis and hastens the onset of steatosis, inflammation and fibrosis

Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of pathologies that includes steatosis, steatohepatitis (NASH) and fibrosis and is strongly associated with insulin resistance and type 2 diabetes. Changes in mitochondrial function are implicated in the pathogenesis of NAFLD, particula...

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Detalles Bibliográficos
Autores principales: Undamatla, Ramya, Fagunloye, Olayemi G., Chen, Jeffrey, Edmunds, Lia R., Murali, Anjana, Mills, Amanda, Xie, Bingxian, Pangburn, Martha M., Sipula, Ian, Gibson, Gregory, Croix, Claudette St., Jurczak, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882688/
https://www.ncbi.nlm.nih.gov/pubmed/36711642
http://dx.doi.org/10.21203/rs.3.rs-2469234/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882688/
https://www.ncbi.nlm.nih.gov/pubmed/36711642
http://dx.doi.org/10.21203/rs.3.rs-2469234/v1

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