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Reduced hepatocyte mitophagy is an early feature of NAFLD pathogenesis and hastens the onset of steatosis, inflammation and fibrosis
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of pathologies that includes steatosis, steatohepatitis (NASH) and fibrosis and is strongly associated with insulin resistance and type 2 diabetes. Changes in mitochondrial function are implicated in the pathogenesis of NAFLD, particula...
Autores principales: | Undamatla, Ramya, Fagunloye, Olayemi G., Chen, Jeffrey, Edmunds, Lia R., Murali, Anjana, Mills, Amanda, Xie, Bingxian, Pangburn, Martha M., Sipula, Ian, Gibson, Gregory, Croix, Claudette St., Jurczak, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882688/ https://www.ncbi.nlm.nih.gov/pubmed/36711642 http://dx.doi.org/10.21203/rs.3.rs-2469234/v1 |
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