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Thiol catalyzed formation of NO-ferroheme regulates canonical intravascular NO signaling

Nitric oxide (NO) is an endogenously produced physiological signaling molecule that regulates blood flow and platelet activation. However, both the intracellular and intravascular diffusion of NO is severely limited by scavenging reactions with hemoglobin, myoglobin, and other hemoproteins, raising...

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Detalles Bibliográficos
Autores principales: DeMartino, Anthony W., Poudel, Laxman, Dent, Matthew R., Chen, Xiukai, Xu, Qinzi, Gladwin, Brendan S., Tejero, Jesús, Basu, Swati, Alipour, Elmira, Jiang, Yiyang, Rose, Jason J., Gladwin, Mark T., Kim-Shapiro, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882697/
https://www.ncbi.nlm.nih.gov/pubmed/36711928
http://dx.doi.org/10.21203/rs.3.rs-2402224/v1