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Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors

Developmentally, the articular joints are derived from lateral plate (LP) mesoderm. However, no study has produced both LP derived prechondrocytes and preosteoblasts from human pluripotent stem cells (hPSC) through a common progenitor in a chemically defined manner. Differentiation of hPSCs through...

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Detalles Bibliográficos
Autores principales: Smith, Christopher A., Humphreys, Paul A., Naven, Mark A., Woods, Steven, Mancini, Fabrizio E., O’Flaherty, Julieta, Meng, Qing-Jun, Kimber, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882893/
https://www.ncbi.nlm.nih.gov/pubmed/36706111
http://dx.doi.org/10.1371/journal.pone.0280024